SummArIzeR is our new R package designed to streamline and smarten enrichment analysis, developed by Anela Tosevska & Marie Brinkmann!
Enrichment results from multiple conditions and multiple databases often produces overlapping and redundant terms, complicating the interpretation and visalization. SummArIzeR makes this easy with the help of AI.

Key features:
– Seamlessly integrates EnrichR for enrichment analysis.
– Supports multiple experimental conditions, with separate handling of up- and downregulated genes.
– Filters and clusters enriched terms using gene overlap and a random walk algorithm.
– Generates prompts for cluster summarization for Claude, ChatGPT and co.
– Outputs publication-ready heatmaps for fast and intuitive visualization.

Try it out, and let us know what you think!
https://lnkd.in/duYgquy7
https://lnkd.in/dwv5B-xz
Hashtag#RStats Hashtag#Bioinformatics Hashtag#GeneExpression Hashtag#PathwayAnalysis Hashtag#EnrichmentAnalysis Hashtag#LLMsInScience Hashtag#OpenSourceScience Hashtag#GPT4 Hashtag#SummArIzeR

Apr 09, 2026

Our team recently participated in the 2nd Research Symposium of the comprehensive center for musculoskeletal diseases (CCMSD) in Vienna.
A well-organized meeting with a clear focus on translational musculoskeletal research and interdisciplinary exchange. This was also a highlight for our team: our two talented PhD students Marie Brinkmann and Laura Hermann presented their work in oral sessions.
Thanks to the organizers for putting together a focused and relevant program, and looking forward to the next edition!

Apr 03, 2026

Congratulation Lisa Göschl, MD, PhD on successfully completing your Habilitation!
This achievement reflects many years of dedicated clinical work, research, and commitment to rheumatology. Well done Lisa, we are proud of you! 

Mar 19, 2026

We recently celebrated 30 years of academic rheumatology in Austria at the Josephinum in Vienna.
For us, this milestone is less about looking back and more about recognizing how far our field has come. Tools like capillaroscopy and ultrasound, once far from routine care, are now central to precision medicine.
What gives us the most confidence for the future is the strong link between research, clinical care, and patients and, as we witnessed during this event, this next chapter is already underway.

Mar 16, 2026

We are very pleased to welcome Sebastian Hasenauer to the clinical department of our Division of Rheumatology, Medical University of Vienna.
Starting a new role always brings fresh perspectives and new energy. I am looking forward to the experience and ideas he will contribute to our team and to the shared work ahead in patient care and clinical research.

Mar 12, 2026

Last Friday, some members of our team joined the networking breakfast organized at the Medizinische Universität Wien on the occasion of International Women’s Day.
Events like this create an important space for exchange, visibility, and support among women in medicine and science. At Medizinische Universität Wien, these conversations are part of a broader effort to strengthen equal opportunities and celebrate women’s careers in research.
Thank you to everyone who contribute to the continued progress towards a more inclusive scientific community.

Mar 09, 2026

Thank you Prof. Riitta Lahesmaa for the kind invitation to present our work in the Immunology Seminar Series of the Turku Bioscience center! It was a pleasure to discuss our current research and exchange ideas with colleagues who approach immune-mediated diseases from complementary perspectives.

Mar 03, 2026

Where does immune protection end and immune-driven damage begin?
This question will be at the center of the upcoming SHIELD Symposium, organized by the SHIELD Securing Host Immunity Eliminaton vs Destruction consortium with strong involvement from our team, including our PhD student Laura Hermann.
By connecting tumor immunology, host immunity, and immune-mediated inflammatory diseases, this meeting will bridge fields that are closely linked but often discussed separately. We warmly invite everyone interested in inflammation and immunity to join us.
More information and registration:
https://lnkd.in/dr9X4cJF

Feb 26, 2026

Last month, our team participated to the Annual General Recess of the Division of Rheumatology, Medical University of Vienna, and what an inspiring few days it was!
It was great to reconnect with colleagues, dive into meaningful discussions about our ongoing research, and reflect on the progress our field continues to make. The energy and ideas shared were a powerful reminder of why we do this work.
We are energized and optimistic as we look ahead to the coming months: advancing science, supporting patients, and continuing to build impact together.

Feb 16, 2026

On this International Day of Women and Girls in Science, we at the Bonelli Lab acknowledge the valuable contributions of women to research and innovation. Their work strengthens our scientific community and advances discovery. We remain committed to fostering an inclusive and supportive environment for current and future scientists.

Feb 11, 2026

We recently took part in the second virtual consortium meeting of the DarkMatter project, a valuable moment to reflect on progress and align on the next scientific steps.
DarkMatter, led by Thomas Vogl, is an ambitious project that aims to uncover the “dark matter” of immune-related non-communicable diseases by exploring how infectious exposures, immune dysregulation, and host factors interact over time and lead to the establishment of auto-immune diseases.
Our team, recently reinforced by our new PostDoc Juan Manuel Sacnun, contributes in particular to questions related to rheumatic diseases and T-lymphocytes, helping to interpret immune and molecular signals in a clinical and disease-specific context. After this successful meeting, we look forward to the next phase of the project with new exciting research avenues to pursue!

Feb 10, 2026

🎉Happy New Year 2026 from the Bonelli Lab!

A major highlight to kick off the year:
We are proud to be a key contributor to the newly funded PHARAO project (PHARmacogenomics of psoriatic Arthritis using multiOmics) supported by EP PerMed – the European Partnership for Personalised Medicine. This ambitious initiative will advance precision medicine in psoriatic arthritis by integrating pharmacogenomics with multi-omics data to better understand treatment responses and tailor care for patients.
Looking ahead in 2026, we are especially excited to forge new collaborations with clinical, computational, and industry partners that amplify our impact, to embrace bold, interdisciplinary approaches that will push the boundaries of what’s possible in personalized rheumatology research and to engage with patients and stakeholders to ensure our science translates into real-world benefits.

Jan 16, 2026

Before the winter break, our team took a short pause from experiments, analyses and manuscripts to enjoy a wonderful evening together at the Altes AKH Christmas Market, just a few steps from our campus.
Between Punsch, lights and plenty of laughter, we also put our coordination skills to the test with a round of Eisstockschießen, one of Austria’s traditional winter pastime. Let’s just say: scientific precision doesn’t always guarantee accuracy on ice but team spirit certainly does!
Wishing all colleagues, collaborators and friends of the lab a peaceful and bright holiday season, and an exciting scientific year ahead!

Dec 15, 2025

While this year’s symposium offered many memorable moments, one stood out especially for our team:
Bianca Luckerbauer was awarded the Lilly Innovation Award (10.000 €) for her outstanding scientific contribution. This is a remarkable achievement and a well-deserved recognition of her creativity, perseverance and commitment to advancing research in Rheumatology & Autoimmunity. Congratulations, Bianca, we are very proud of you!

Dec 03, 2025

What a memorable ÖGR Jahrestagung 2025!
A heartfelt thank you to the Österreichische Gesellschaft für Rheumatologie & Rehabilitation (ÖGR) and especially to Helga Lechner-Radner for the exceptional organization, vision and commitment that shaped this year’s symposium. Three days full of exchange, learning and inspiration and a reflection of the strength of rheumatology in Austria.
We are particularly proud of the outstanding presence of our team: from insightful poster presentations to expertly chaired sessions, your contributions showcased the depth, curiosity and collaborative spirit that drive our research forward. And more generally, a sincere thank you to everyone who engaged with our work, shared ideas and helped create such a collegial atmosphere. Already looking forward to next year!

Dec 01, 2025

The IAI SHIELD Securing Host Immunity Eliminaton vs Destruction doctoral consortium, led by Maria Sibilia gathered in Hungary for a two-day retreat: an inspiring opportunity for scientific exchange, strategic discussions, and team building, in which Michael, Laura and Bianca joined to represent our group.
Thanks to a great panel of participants and a flawless organization, Michael, Laura and Bianca could participate to stimulating discussions exploring how the immune system balances protection and pathology, from molecular mechanisms to clinical translation. Until next year!

Nov 14, 2025

Michael was recently a guest on the Hörgang / Springer Medizin podcast, where he dove deep into the future of rheumatology, from leveraging artificial intelligence to envisioning a “reset” of the immune system in autoimmune disease.
In his conversation, he explored:
– The paradigm shift from trial-and-error prescribing to precision and personalized immunotherapy
– Using high-throughput microscopy + AI to predict which treatments will work for individual patients (and do so fast)
– How cellular therapies (e.g. CAR-T, regulatory T cells) may one day enable not just control, but true resetting of the immune system
– The challenges and opportunities ahead: translation, collaboration, and training the next generation

If you are interested in how cutting-edge technology, immunology, and clinical translation intersect in rheumatology, we invite you to listen (in German): https://www.springermedizin.at/meduni-wien/rheumatologie/reset-immunsystem/51483808

Oct 10, 2025

A New Chapter Begins: as of August 2025, Michael has taken on the role of Professor for Experimental Rheumatology at the Medical University of Vienna (https://www.meduniwien.ac.at/web/en/ueber-uns/news/2025/news-in-september-2025/michael-bonelli-takes-up-professorship-in-experimental-rheumatology/). As director of the Basic and Translational Science Unit of the Division of Rheumatology, Medical University of Vienna (Internal Medicine III), he will now lead and expand efforts in translational rheumatology research.

Why this matters:
– Bridging discovery and care: Experimental Rheumatology serves as a vital link between laboratory research and clinical therapeutics for patients with autoimmune and chronic inflammatory diseases .
– Innovating precision medicine: Our team’s focus on molecular and cellular disease mechanisms empowers us to develop next-generation diagnostics and therapeutic interventions tailored to individual patient profiles.
– Exploring cellular immunotherapies: We are particularly excited about advancing breakthrough approaches such as cell-based therapies – including CAR T cell and regulatory T cell therapies – which hold the potential to go beyond disease control and offer, for the first time, a truly curative perspective for patients with autoimmune diseases.

Michael’s motivation and vision as newly appointed professor are clear: transform foundational research into tangible clinical innovations. From stratifying patients earlier to identifying new therapeutic targets, the goal is clear: personalized care powered by translational science.

Sep 04, 2025

Our team has been strongly represented at this year’s International Congress of Immunology (International Union of Immunological Societies (IUIS) 2025) that took place last week, right here in our home city of Vienna! Check out below our contributions:

Two oral presentations from Mirjam Dellinger & Lisabeth Emilius:
– Mirjam presented how cytokine-primed fibroblast–immune cell interactions drive immune activation and pathotype development in rheumatoid arthritis. (abstract: https://iuis2025.abstractserver.com/program/#/details/presentations/2814)
– Lisabeth presented advanced imaging-based ex vivo immunoprofiling to stratify RA patients and move toward functional personalized medicine. (abstract: https://iuis2025.abstractserver.com/program/#/details/presentations/615)

Three Poster presentations from Marie Brinkmann, Teresa Preglej and Bianca Luckerbauer:
– Marie presented her work on Epigenetic inhibitors: a novel treatment for rheumatoid arthritis (Poster II.474) (abstract: https://iuis2025.abstractserver.com/program/#/details/presentations/726)
– Teresa presented her work on Time-resolved immune dynamics in rheumatoid arthritis under methotrexate therapy (Poster II.074) (abstract: https://iuis2025.abstractserver.com/program/#/details/presentations/885)
– Bianca presented her work on the Molecular control of regulatory T cells by nuclear factor interleukin-3 regulated (Poster II.067) (abstract: https://iuis2025.abstractserver.com/program/#/details/presentations/534)

Finally, in addition to her poster presentation, Teresa co-chaired two sessions:
– Autoimmunity Poster Walk
– Autoimmune diseases Part II (Abstract Session)

A huge shout-out to all our presenters for their outstanding science, energy, and teamwork!
We also thank our international colleagues for the inspiring discussions and collaborations, hosting the global immunology community in Vienna has been a true highlight – see you all at the next IUIS!

Aug 27, 2025

We’re proud that so many members of the Bonelli Lab joined KinderUni 2025 to inspire Vienna’s youngest minds!
Our team helped children explore the fascinating world of autoimmunity — what happens “wenn der Körper sich selbst angreift”, when the immune system turns against the body.

🔬 Through interactive games and creative conversations, they showed how science can be both powerful and playful.
A heartfelt thank you to our team members Bianca Luckerbauer, Marie Brinkmann, Lisabeth Emilius, Laura Hermann, Teresa Preglej, and Melanie Acosta and other participating members of our Division of Rheumatology, Jessica Lange, Caroline Dürrschmid & Daniela Sieghart, who brought their energy and passion to the event.

Let’s keep sparking curiosity – one future scientist at a time!
🔗 Learn more: https://kinderuni-anmeldung.at/event.php?event_id=5964

Jul 21, 2025