Inflammatory rheumatic disorders such as Rheumatoid Arthritis are driven by local inflammatory processes at the site of inflammation. These processes involve a crosstalk of multiple cell types in the synovial tissue that drives the activation of immune cells.  Our lab aims to understand the importance of these cellular crosstalks (structural immunity) as a driver of synovial inflammation with the goal to develop new therapeutic strategies to prevent tissue inflammation and damage. Our research in this field most recently led to our characterization of the cellular cross-talks in rheumatoid arthritis.